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Ships within 48 hours ยท Estimated delivery Jul 5 - Jul 10
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Description
Pacific Blue Mouse Anti-Human Perforin Antibody (S-3064)Product Specification Host Mouse Antigen Perforin Synonyms Perforin 1; P1; Cytolysin; Lymphocyte pore forming protein (PFP); PFP; PRF1 Location Secreted, Cell membrane Accession P14222 Clone Number S 3064 Antibody Type Mouse mAb Isotype IgG2b,k Application ICFCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300
Product Specification
| Host | Mouse |
| Antigen | Perforin |
| Synonyms | Perforin-1; P1; Cytolysin; Lymphocyte pore-forming protein (PFP); PFP; PRF1 |
| Location | Secreted, Cell membrane |
| Accession | P14222 |
| Clone Number | S-3064 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2b,k |
| Application | ICFCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | Pacific Blue |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 ยฐC as supplied |
Dilution
| application | dilution | species |
| ICFCM | 5ฮผl per million cells in 100ฮผl volume | Hu |
Background
Perforin is a crucial protein involved in the immune response, primarily produced by cytotoxic T lymphocytes and natural killer cells. It functions as a pore-forming protein, inserting itself into the membranes of target cells, such as virus-infected or cancerous cells. Once integrated, perforin creates pores that disrupt the cell membrane's integrity, leading to osmotic lysis and ultimately killing the target cell. This mechanism is essential for the immune system's ability to eliminate harmful cells and maintain homeostasis.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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